Brief Information of the Compound and Protein
Compound Name
Trans-8-cyclopropyl-6-methyl-2,3,3a,4-tetrahydro-1H-pyrrolo[3,4-c]isoquinolin-5(9bH)-one hydrochloride
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PubChem ID
CID: 69056262
SID: 163511200
Canonical SMILES
Cc1cc(C2CC2)cc2c1C(=O)N[C@H]1CNC[C@H]21.Cl
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Compound Formula C15H19ClN2O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2B
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P41595
Gene Name
HTR2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000065 HEK293-EBNA Homo sapiens (Human)  2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
Ki = 177 nM
   TI
   LI
   LO
   TS