Brief Information of the Compound and Protein
Compound Name
 Compound Info 
CAS_114798-26-4
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 PubChem ID
CID: 3961
SID: 14758375
Canonical SMILES
CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
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Compound Formula C22H23ClN6O
Compound Structure
Protein Name
 Protein Info 
Type-1 angiotensin II receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Angiotensin receptor
Uniprot ID
P30556
Gene Name
AGTR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 28.6 nM
   TI
   LI
   LO
   TS
2
Ki = 5.012 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5.623 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.33 nM
2 IC50 = 8 nM
3 IC50 = 16.2 nM
4 IC50 = 28 nM
5 IC50 = 350 nM