Brief Information of the Compound and Protein
Compound Name
3-cyclohexyl-5-oxa-4,8,10-triazatricyclo[7.3.0.02,6]dodeca-1(12),2,6,8,10-pentaene
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PubChem ID
SID: 163514014
Canonical SMILES
C1CCC(CC1)c1noc2cnc3[nH]ccc3c12
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Compound Formula C14H15N3O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
EC50 = 430 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM