Brief Information of the Compound and Protein
Compound Name
12-cyclohexyl-1,5,7,10,11-pentazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaene
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PubChem ID
CID: 136013449
SID: 111325471
Canonical SMILES
C1CCC(CC1)c1nnc2cnc3[nH]ccc3n12
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Compound Formula C13H15N5
Compound Structure
Protein Name
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1 Homo sapiens (Human)  1
1
EC50 = 350 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM