Brief Information of the Compound and Protein
Compound Name
1-(4-Amino-phenyl)-3-(3-benzo[1,3]dioxol-5-yl-4-oxo-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl)-urea
    Show/Hide
PubChem ID
CID: 44446962
Canonical SMILES
Nc1ccc(NC(=O)Nc2cccc3-c4[nH]nc(c4C(=O)c23)-c2ccc3OCOc3c2)cc1
    Show/Hide
Compound Formula C24H17N5O4
Compound Structure
Protein Name
Hypoxia-inducible factor 1-alpha
Protein Classification
Transcription factor
Uniprot ID
Q16665
Gene Name
HIF1A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 214 nM
   TI
   LI
   LO
   TS