Brief Information of the Compound and Protein
Compound Name
N-[(2R)-3-[4-(4-chloro-2-methylphenoxy)piperidin-1-yl]-2-hydroxypropyl]-7-fluoro-1-oxo-2H-isoquinoline-4-carboxamide
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PubChem ID
CID: 59295984
SID: 163525678
Canonical SMILES
Cc1cc(Cl)ccc1OC1CCN(C[C@H](O)CNC(=O)c2c[nH]c(=O)c3cc(F)ccc23)CC1
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Compound Formula C25H27ClFN3O4
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 12.59 nM
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