Brief Information of the Compound and Protein
Compound Name
N-[(2R)-3-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-2-hydroxypropyl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxamide
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PubChem ID
CID: 59296111
SID: 163526122
Canonical SMILES
O[C@H](CNC(=O)c1cn[nH]c1C(F)(F)F)CN1CCC(CC1)Oc1ccc(Cl)c(Cl)c1
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Compound Formula C19H21Cl2F3N4O3
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 15.85 nM
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