Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[3-[(1R,3R)-3-hydroxycyclohexyl]-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-4-yl]methyl]methanesulfonamide
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 PubChem ID
CID: 71461405
SID: 163525440
Canonical SMILES
CS(=O)(=O)NCc1nc2cnc3[nH]ccc3c2n1[C@@H]1CCC[C@@H](O)C1
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Compound Formula C16H21N5O3S
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 2200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.2 nM