Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-fluoro-3-[3-(5-fluoropyridin-3-yl)phenyl]-3-pyridin-4-ylisoindol-1-amine
    Show/Hide
 PubChem ID
CID: 46206294
SID: 96060488
Canonical SMILES
NC1=NC(c2cccc(F)c12)(c1ccncc1)c1cccc(c1)-c1cncc(F)c1
    Show/Hide
Compound Formula C24H16F2N4
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 25.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 137 nM