Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-benzyl-5-methyl-2-(3-pyrimidin-5-ylphenyl)imidazol-4-amine
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 PubChem ID
CID: 49869174
SID: 104544103
Canonical SMILES
CC1=N[C@](Cc2ccccc2)(N=C1N)c1cccc(c1)-c1cncnc1
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Compound Formula C21H19N5
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2600 nM