Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[3-(5-chloropyridin-3-yl)phenyl]-2-cyclopropyl-5-methylimidazol-4-amine
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 PubChem ID
CID: 49869312
SID: 104544237
Canonical SMILES
CC1=NC(N=C1N)(C1CC1)c1cccc(c1)-c1cncc(Cl)c1
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Compound Formula C18H17ClN4
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000004 SH-SY5Y
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 310 nM