Brief Information of the Compound and Protein
Compound Name
(2S)-3-amino-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-2-[4-(trifluoromethyl)phenyl]propan-1-one
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PubChem ID
CID: 70676316
Canonical SMILES
C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H](CN)c3ccc(cc3)C(F)(F)F)c12
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Compound Formula C22H26F3N5O2
Compound Structure
Protein Name
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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AGC protein kinase group
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AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000141 LNCaP Homo sapiens (Human)  1
1
IC50 = 603 nM
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