Brief Information of the Compound and Protein
Compound Name
4-(5-Chloro-8-methyl-9H-1,2,3a,4,9,10-hexaaza-cyclopenta[b]fluoren-3-ylmethyl)-phenol
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PubChem ID
CID: 135537650
SID: 16856443
Canonical SMILES
Cc1ccc(Cl)c2c1[nH]c1nc3nnc(Cc4ccc(O)cc4)n3nc12
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Compound Formula C18H13ClN6O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 107 nM