Brief Information of the Compound and Protein
Compound Name
6-(4-fluorophenyl)-3-(1H-pyrazolo[3,4-d]pyrimidin-4-ylsulfanylmethyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazine
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PubChem ID
CID: 70677395
SID: 160642600
Canonical SMILES
Fc1ccc(cc1)-c1cnc2nnc(CSc3ncnc4n[nH]cc34)n2n1
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Compound Formula C16H10FN9S
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 520 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 188 nM