Brief Information of the Compound and Protein
Compound Name
3-[(4-methoxyphenyl)methyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
    Show/Hide
PubChem ID
CID: 70677533
SID: 160642765
Canonical SMILES
COc1ccc(Cn2nnc3ncc(nc23)-c2cnn(C)c2)cc1
    Show/Hide
Compound Formula C16H15N7O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 51 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 82 nM