Brief Information of the Compound and Protein
Compound Name
6-[[5-[1-(2-pyrrolidin-1-ylethyl)pyrazol-4-yl]triazolo[4,5-b]pyrazin-3-yl]methyl]quinoline
    Show/Hide
PubChem ID
CID: 59341868
SID: 160642930
Canonical SMILES
C(Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1)N1CCCC1
    Show/Hide
Compound Formula C23H23N9
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 43.2 nM