Brief Information of the Compound and Protein
Compound Name
3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine
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PubChem ID
CID: 70677534
SID: 160642767
Canonical SMILES
Cn1cc(cn1)-c1cnc2nnn(Cc3ccc4OCCOc4c3)c2n1
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Compound Formula C17H15N7O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 146 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 35 nM