Brief Information of the Compound and Protein
Compound Name
1-[2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethyl]pyrrolidin-2-one
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PubChem ID
CID: 59341929
SID: 160642931
Canonical SMILES
O=C1CCCN1CCn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
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Compound Formula C23H21N9O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 91 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 61.7 nM