Brief Information of the Compound and Protein
Compound Name
3-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methylsulfanyl]-5-(methylamino)-1,2-thiazole-4-carboxamide
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PubChem ID
CID: 70677396
SID: 160642601
Canonical SMILES
CNc1snc(SCc2nnc3ncc(nn23)-c2ccc(F)cc2)c1C(N)=O
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Compound Formula C16H13FN8OS2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 2 nM