Brief Information of the Compound and Protein
Compound Name
7-[[6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl]methoxy]thieno[3,2-b]pyridine
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PubChem ID
CID: 70677258
SID: 160642441
Canonical SMILES
Fc1ccc(cc1)-c1cnc2nnc(COc3ccnc4ccsc34)n2n1
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Compound Formula C18H11FN6OS
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 > 2500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 425 nM