Brief Information of the Compound and Protein
Compound Name
N,N-dimethyl-2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanamine
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PubChem ID
CID: 45381018
SID: 93372686
Canonical SMILES
CN(C)CCn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
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Compound Formula C21H21N9
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 20 nM