Brief Information of the Compound and Protein
Compound Name
6-(4-fluorophenyl)-3-[(4-methoxyphenyl)methyl]-[1,2,4]triazolo[4,3-b][1,2,4]triazine
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PubChem ID
CID: 70677253
SID: 160642436
Canonical SMILES
COc1ccc(Cc2nnc3ncc(nn23)-c2ccc(F)cc2)cc1
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Compound Formula C18H14FN5O
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 113 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 69 nM