Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol
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 PubChem ID
CID: 17754438
SID: 29212271
Canonical SMILES
OCCn1cc(cn1)-c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1
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Compound Formula C19H16N8O
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 0.3 nM
2 IC50 = 4 nM
3 IC50 = 4.8 nM
4 IC50 = 50.12 nM
5 Kd = 4.5 nM
6 Ki = 4.8 nM
7 Ki = 5 nM