Brief Information of the Compound and Protein
Compound Name
1-[5-(4-amino-7-methylpyrrolo[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-(3-chlorophenyl)ethanone
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PubChem ID
CID: 53469449
SID: 126495736
Canonical SMILES
Cn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(Cl)c2)c2c(N)ncnc12
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Compound Formula C23H20ClN5O
Compound Structure
Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PEK family
>
Other protein kinase PEK subfamily
Uniprot ID
Q9NZJ5
Gene Name
EIF2AK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 < 30 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.2 nM