Brief Information of the Compound and Protein
Compound Name
1-[5-(4-aminothieno[3,2-c]pyridin-3-yl)-2,3-dihydroindol-1-yl]-2-phenylethanone
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PubChem ID
CID: 53466728
SID: 126492946
Canonical SMILES
Nc1nccc2scc(-c3ccc4N(CCc4c3)C(=O)Cc3ccccc3)c12
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Compound Formula C23H19N3OS
Compound Structure
Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PEK family
>
Other protein kinase PEK subfamily
Uniprot ID
Q9NZJ5
Gene Name
EIF2AK3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 > 300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11.7 nM