Brief Information of the Compound and Protein
Compound Name
4-[4-(3,4-dichlorophenoxy)piperidin-1-yl]-N-(4-methylphenyl)sulfonylpiperidine-1-carboxamide
    Show/Hide
PubChem ID
CID: 11753159
Canonical SMILES
Cc1ccc(cc1)S(=O)(=O)NC(=O)N1CCC(CC1)N1CCC(CC1)Oc1ccc(Cl)c(Cl)c1
    Show/Hide
Compound Formula C24H29Cl2N3O4S
Compound Structure
Protein Name
Histamine H1 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Histamine receptor
Uniprot ID
P35367
Gene Name
HRH1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 31.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM
2 Ki = 31.62 nM