Brief Information of the Compound and Protein
Compound Name
methyl (2S)-8',10-dihydroxy-5',7'-dimethoxy-4',9,9'-trioxospiro[3,4-dihydropyrano[4,3-g]chromene-2,2'-3H-benzo[f][1]benzofuran]-7-carboxylate
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PubChem ID
CID: 5464074
SID: 15781229
Canonical SMILES
COC(=O)c1cc2cc3CC[C@]4(CC5=C(O4)C(=O)c4c(O)c(OC)cc(OC)c4C5=O)Oc3c(O)c2c(=O)o1
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Compound Formula C27H20O12
Compound Structure
Protein Name
Telomerase reverse transcriptase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
O14746
Gene Name
TERT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
IC50 = 1320 nM
   TI
   LI
   LO
   TS
2
IC50 = 1530 nM
   TI
   LI
   LO
   TS
CL000002 K-562 Homo sapiens (Human)  1
1
IC50 = 3060 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3000 nM