Brief Information of the Compound and Protein
Compound Name
[2-3H]-3-Fluoro-5-[3-(5-fluoropyridin-2-yl)-1,2,4-oxadiazol-5-yl]-benzonitrile
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PubChem ID
CID: 71460569
Canonical SMILES
[3H]c1c(F)cc(-c2nc(-c3ccc(F)cn3)no2)cc1C#N
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Compound Formula C14H6F2N4O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P41594
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
Kd = 2.25 nM
   TI
   LI
   LO
   TS
2
Kd = 3.8 nM
   TI
   LI
   LO
   TS
3
Kd = 5.5 nM
   TI
   LI
   LO
   TS
4
Kd = 7.2 nM
   TI
   LI
   LO
   TS