Brief Information of the Compound and Protein
Compound Name
6-[5-(3-cyano-5-fluorophenyl)-1,2,4-oxadiazol-3-yl]pyridine-3-carbonitrile
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PubChem ID
CID: 9879103
SID: 14845123
Canonical SMILES
Fc1cc(cc(c1)-c1nc(no1)-c1ccc(cn1)C#N)C#N
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Compound Formula C15H6FN5O
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 3.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14.5 nM