Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(3S,4R)-3-fluoropiperidin-4-yl]-4-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene
    Show/Hide
 PubChem ID
CID: 60170770
SID: 144120093
Canonical SMILES
Cc1nc2cnc3[nH]ccc3c2n1[C@@H]1CCNC[C@@H]1F
    Show/Hide
Compound Formula C14H16FN5
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 490 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 9.3 nM