Brief Information of the Compound and Protein
Compound Name
N-[(2S,3R)-4-[[2-(2,2-dimethylpropyl)-6,6-dimethyl-5,7-dihydro-4H-indazol-4-yl]amino]-3-hydroxy-1-phenylbutan-2-yl]acetamide
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PubChem ID
CID: 71460382
Canonical SMILES
CC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC(C)(C)Cc2nn(CC(C)(C)C)cc12
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Compound Formula C26H40N4O2
Compound Structure
Protein Name
Beta-secretase 1
Protein Classification
Enzyme
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Protease
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Aspartic protease
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Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 65 nM
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