Brief Information of the Compound and Protein
Compound Name
 Compound Info 
methyl 3-[[4-[[(1R,3S)-5-amino-2-adamantyl]carbamoyl]phenyl]methyl]-4-oxo-1-phenyl-1,8-naphthyridine-2-carboxylate
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 PubChem ID
SID: 163434067
Canonical SMILES
COC(=O)c1c(Cc2ccc(cc2)C(=O)N[C@H]2[C@H]3C[C@H]4C[C@@H]2C[C@](N)(C4)C3)c(=O)c2cccnc2n1-c1ccccc1
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Compound Formula C34H34N4O4
Compound Structure
Protein Name
 Protein Info 
Mitogen-activated protein kinase 8
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CMGC protein kinase group
>
CMGC protein kinase MAPK family
>
CMGC protein kinase JNK subfamily
Uniprot ID
P45983
Gene Name
MAPK8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000505 HK-2 [Human kidney]
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 21900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 49 nM