Brief Information of the Compound and Protein
Compound Name
 Compound Info 
[(2S)-1-propan-2-ylpyrrolidin-2-yl]-[4-(3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaen-3-yl)piperidin-1-yl]methanone
    Show/Hide
 PubChem ID
CID: 53341544
SID: 125006531
Canonical SMILES
CC(C)N1CCC[C@H]1C(=O)N1CCC(CC1)n1cnc2cnc3[nH]ccc3c12
    Show/Hide
Compound Formula C21H28N6O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
P23458
Gene Name
JAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000128 TF-1
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 > 8800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 22 nM