Brief Information of the Compound and Protein
Compound Name
US10155972, Compound LM10
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PubChem ID
CID: 135743630
SID: 125320180
Canonical SMILES
Fc1ccc2c(\C=C\c3nnn[nH]3)c[nH]c2c1
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Compound Formula C11H8FN5
Compound Structure
Protein Name
Tryptophan 2,3-dioxygenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P48776
Gene Name
TDO2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000784 P815B Mus musculus (Mouse)  2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
IC50 = 17000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1960 nM