Brief Information of the Compound and Protein
Compound Name
6-[2-(3-cyano-5-fluorophenyl)ethynyl]pyridine-2-carbonitrile
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PubChem ID
CID: 70689178
SID: 163438233
Canonical SMILES
Fc1cc(cc(c1)C#Cc1cccc(n1)C#N)C#N
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Compound Formula C15H6FN3
Compound Structure
Protein Name
Metabotropic glutamate receptor 5
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31424
Gene Name
GRM5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000050 HEK293-A Homo sapiens (Human)  1
1
IC50 = 9 nM
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