Brief Information of the Compound and Protein
Compound Name
(S)-6-(4-(2-(dimethylamino)ethoxy)phenyl)-5-phenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine
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PubChem ID
CID: 44438318
SID: 163437502
Canonical SMILES
CN(C)CCOc1ccc(cc1)-c1oc2ncnc(NC[C@@H]3CCCO3)c2c1-c1ccccc1
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Compound Formula C27H30N4O3
Compound Structure
Protein Name
Activated CDC42 kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ack family
Uniprot ID
Q07912
Gene Name
TNK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000023 BTI-Tn-5B1-4 Trichoplusia ni (Cabbage looper)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11 nM