Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3R,11bS)-2-[[(1R)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl]-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine;hydrochloride
    Show/Hide
 PubChem ID
CID: 10219
SID: 15455076
Canonical SMILES
CC[C@H]1CN2CCc3cc(OC)c(OC)cc3[C@@H]2C[C@@H]1C[C@H]1NCCc2cc(OC)c(OC)cc12
    Show/Hide
Compound Formula C29H40N2O4
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000167 NIH-3T3-G185
 Cell Line Info 
Mus musculus (Mouse)  4
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
2
IC50 = 9200 nM
   TI
   LI
   LO
   TS
3
IC50 = 9600 nM
   TI
   LI
   LO
   TS
4
IC50 = 35100 nM
   TI
   LI
   LO
   TS