Brief Information of the Compound and Protein
Compound Name
 Compound Info 
10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)phenothiazine;hydrochloride
    Show/Hide
 PubChem ID
CID: 5566
SID: 14904043
Canonical SMILES
CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1
    Show/Hide
Compound Formula C21H24F3N3S
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000167 NIH-3T3-G185
 Cell Line Info 
Mus musculus (Mouse)  3
1
IC50 = 6300 nM
   TI
   LI
   LO
   TS
2
IC50 = 7200 nM
   TI
   LI
   LO
   TS
3
IC50 = 10900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 6500 nM