Brief Information of the Compound and Protein
Compound Name
N-(2-methylpropyl)-N-[4-(1,1,1-trifluoro-2-hydroxy-4-pyridin-2-ylbut-3-yn-2-yl)phenyl]benzenesulfonamide
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PubChem ID
CID: 21037789
SID: 163469486
Canonical SMILES
CC(C)CN(c1ccc(cc1)C(O)(C#Cc1ccccn1)C(F)(F)F)S(=O)(=O)c1ccccc1
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Compound Formula C25H23F3N2O3S
Compound Structure
Protein Name
Oxysterols receptor LXR-beta
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 3
Uniprot ID
P55055
Gene Name
NR1H2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3800 nM