Brief Information of the Compound and Protein
Compound Name
3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)propanoic acid
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PubChem ID
CID: 46941175
SID: 99449553
Canonical SMILES
Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
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Compound Formula C23H23NO2
Compound Structure
Protein Name
Free fatty acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Free fatty acid receptor
Uniprot ID
O14842
Gene Name
FFAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000094 1321N1 Homo sapiens (Human)  4
1
EC50 = 14.79 nM
   TI
   LI
   LO
   TS
2
EC50 = 18.62 nM
   TI
   LI
   LO
   TS
3
EC50 = 34.67 nM
   TI
   LI
   LO
   TS
4
EC50 = 44.67 nM
   TI
   LI
   LO
   TS
CL000460 Flp-In-T-REx-293 Homo sapiens (Human)  2
1
EC50 = 18.62 nM
   TI
   LI
   LO
   TS
2
Ki = 5.888 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 11.22 nM
   TI
   LI
   LO
   TS
2
EC50 = 12.88 nM
   TI
   LI
   LO
   TS