Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(4S,8E)-4-[(1R)-2-[(3-tert-butylphenyl)methylamino]-1-hydroxyethyl]-2,13-dioxo-6-oxa-3,12-diazabicyclo[12.3.1]octadeca-1(17),8,14(18),15-tetraen-16-yl]-N-methylmethanesulfonamide
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 PubChem ID
CID: 70694546
Canonical SMILES
CN(c1cc2cc(c1)C(=O)N[C@@H](COC\C=C\CCNC2=O)[C@H](O)CNCc1cccc(c1)C(C)(C)C)S(C)(=O)=O
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Compound Formula C30H42N4O6S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 4.6 nM
   TI
   LI
   LO
   TS