Brief Information of the Compound and Protein
Compound Name
3-[5-(4-chlorophenyl)furan-2-yl]-5-(1H-imidazol-5-yl)-4-(4-piperazin-1-ylphenyl)-5H-1,2,4-oxadiazole
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PubChem ID
CID: 70692331
Canonical SMILES
Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cnc[nH]1
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Compound Formula C25H23ClN6O2
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  1
1
EC50 = 2400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 70 nM