Brief Information of the Compound and Protein
Compound Name
N-[N'-[3-[[4-(4-fluorophenyl)benzoyl]amino]phenyl]carbamimidoyl]-3,4,5-trimethoxybenzamide
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PubChem ID
CID: 136210510
SID: 110268518
Canonical SMILES
COc1cc(cc(OC)c1OC)C(=O)NC(N)=Nc1cccc(NC(=O)c2ccc(cc2)-c2ccc(F)cc2)c1
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Compound Formula C30H27FN4O5
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II Mus musculus (Mouse)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS