Brief Information of the Compound and Protein
Compound Name
N-[(3-imidazo[1,2-a]pyridin-2-ylphenyl)carbamothioyl]-3,4,5-trimethoxybenzamide
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PubChem ID
CID: 57326302
SID: 136328284
Canonical SMILES
COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1cccc(c1)-c1cn2ccccc2n1
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Compound Formula C24H22N4O4S
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II Mus musculus (Mouse)  1
1
IC50 = 820 nM
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   LI
   LO
   TS