Brief Information of the Compound and Protein
Compound Name
3,4,5-trimethoxy-N-[[4-methyl-3-(phenylcarbamoyl)phenyl]carbamothioyl]benzamide
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PubChem ID
CID: 57326484
SID: 136328488
Canonical SMILES
COc1cc(cc(OC)c1OC)C(=O)NC(=S)Nc1ccc(C)c(c1)C(=O)Nc1ccccc1
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Compound Formula C25H25N3O5S
Compound Structure
Protein Name
Protein smoothened
Protein Classification
Membrane receptor
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Frizzled family G protein-coupled receptor
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Smoothened receptor (frizzled family GPCR)
Uniprot ID
Q99835
Gene Name
SMO
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000426 Shh Light II Mus musculus (Mouse)  1
1
IC50 = 1800 nM
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