Brief Information of the Compound and Protein
Compound Name
5-(3-methyl-1,2-thiazol-5-yl)-3-(quinolin-6-ylmethyl)triazolo[4,5-c]pyridin-4-one
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PubChem ID
CID: 58270290
Canonical SMILES
Cc1cc(sn1)-n1ccc2nnn(Cc3ccc4ncccc4c3)c2c1=O
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Compound Formula C19H14N6OS
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM