Brief Information of the Compound and Protein
Compound Name
5-(3,5-difluorophenyl)-3-[(3-methoxyquinolin-6-yl)methyl]triazolo[4,5-c]pyridin-4-one
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PubChem ID
CID: 44513258
SID: 85847858
Canonical SMILES
COc1cnc2ccc(Cn3nnc4ccn(-c5cc(F)cc(F)c5)c(=O)c34)cc2c1
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Compound Formula C22H15F2N5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM