Brief Information of the Compound and Protein
Compound Name
N-[3-fluoro-4-(7-methoxyquinolin-4-yl)oxyphenyl]-5-methyl-3-oxo-1-[(2-oxo-1,3-oxazolidin-5-yl)methyl]-2-phenylpyrazole-4-carboxamide
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PubChem ID
CID: 70690073
Canonical SMILES
COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC5CNC(=O)O5)n(-c5ccccc5)c4=O)cc3F)ccnc2c1
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Compound Formula C31H26FN5O6
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 116 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 4.4 nM