Brief Information of the Compound and Protein
Compound Name
N-[5-(6,7-dimethoxyquinolin-4-yl)oxypyridin-2-yl]-1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carboxamide
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PubChem ID
CID: 70692216
Canonical SMILES
COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)nc3)c2cc1OC
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Compound Formula C28H25N5O5
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000048 PC-3 Homo sapiens (Human)  1
1
IC50 = 71.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.9 nM