Brief Information of the Compound and Protein
Compound Name
2-methylsulfanyl-3-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-5-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
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PubChem ID
CID: 70685442
Canonical SMILES
CSc1nn2c(nc(cc2=O)N2CCOCC2)n1Cc1cccc(c1C)C(F)(F)F
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Compound Formula C19H20F3N5O2S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000196 MDA-MB-468 Homo sapiens (Human)  1
1
IC50 = 5.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.4 nM